Accutane is actually a very powerful drug.Though ISOTREX is known as the tropical version of Accutane, the results may not be the same.
In USA, ISOTREX is not available yet.The exact reason is unknown.But I used ISOTREX without the problem.It lowered my sebum production.And transformed my skin from super oily to normal "oily".Please consider that was my personal experience.
ISOTREX is made by Stiefel, one of the oldest dermatological companies.